This talk will focus on the chemotherapy resistance mechanism in ovarian cancer. The speaker will present findings on a novel protein kinase that critically contributes to paclitaxel resistance in ovarian cancer. The talk will highlight how AAK1 regulates paclitaxel sensitivity and demonstrate that AAK1 as a promising target to improve paclitaxel efficacy in ovarian cancer.
Learning Objectives:
Reveal a novel protein kinase signaling in mediating taxane resistance in ovarian cancer.
Identify the effect of small molecular AAK1 inhibitors in taxane resistant ovarian cancer.
Discuss the potential of AAK1 as a biomarker in predicting taxane resistance.
