Discovery and Basic Research
Paolo Lecchi, Ph.D.
Scientist
USP
Rockville, Maryland
Brian Domanski
Strategic Collaborations Scientist - Pharmaceuticals
Shimadzu Scientific Instruments, Inc.
Columbia, Maryland
Niray Bhakta, MS
Graduate Teaching Assistant
The University of Texas at Arlington
Description: Drug development and analysis across modalities relies on separation technologies, from synthesis and purification to ADME/DMPK to final QA/QC. While SFC has long played a role in Pharma and Biopharma, the versatility, ease of use, and complementarity of tools for the technique are experiencing a renaissance. SFC can reduce or eliminate use of hazardous solvents, creating sustainable, efficient separations that minimize potential harm to users and the environment. In this session, we examine SFC as alternative for normal phase monographs, AQbD method development tools to optimize separations of peptide therapeutics, and other emerging uses of SFE-SFC and SFC-MS. Join us for a discussion of how SFC can provide faster, greener, and better separations for therapeutics from development to delivery.