Formulation and Delivery
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Elena Draganoiu, PhD
Global Technical Business Development Director, Pharmaceuticals & Nutraceuticals
Lubrizol
Brecksville, Ohio
Liliana Miinea, PhD
Global Technology Manager
Lubrizol
Brecksville, Ohio
Description: Advances in drug discovery have increased the number of poorly soluble compounds, driving the need for effective solubilizers across drug development stages and administration routes (oral, parenteral). This presentation reviews novel and established solubilizers for approved or experimental drug molecules, emphasizing formulation parameters, screening methods, in vitro and animal data, and regulatory considerations. Recommendations will be offered for excipient selection to support progression from early trials to late-stage clinical development towards drug approval.