Enhancing Formulation Development with Algorithm-Based Excipient Selection Platform

Tuesday, November 11, 2025

3:00 PM - 4:00 PM CT

Location:360 Stage #3, Exhibit Hall

Sponsored By

Partner Presentation Speaker(s)

HS

Harsh Shah, Ph.D.

Senior Scientist, Pharma Solutions
BASF Corporation
Tarrytown, New York
Felicitas Guth, PhD (she/her/hers)

Head of Development, Pharma Solutions
BASF SE
Ludwigshafen am rhein, Rheinland-Pfalz, Germany

Description: Drug–polymer miscibility is crucial for stable amorphous solid dispersions (ASDs) to enhance solubility and bioavailability of poorly soluble drugs. Poor miscibility risks phase separation and reduced performance. Digital formulation tools can play a crucial role in enabling rational excipient selection, providing miscibility prediction, and expediting data-driven formulation design. A case study with Hot Melt Extrusion (HME) highlights how virtual formulation assistants can streamline polymer selection, improves stability, and reduces developmental time and risk in ASD development.

Learning Objectives:

Experimental methods to assess drug-polymer miscibility.
How in silico screening tools can accelerate formulation decisions.
Case Study: Formulating an ASD via Hot Melt Extrusion with a virtual formulation assistant.