.jpg "Ashlee D. Brunaugh, PharmD, PhD photo")
Assistant Professor
University of Michigan
Ann Arbor, Michigan
Dr. Ashlee Brunaugh, PharmD, PhD is an Assistant Professor of Pharmaceutical Sciences at the University of Michigan. Her research focuses on understanding and controlling the behavior of drugs, proteins, and microbes in complex viscoelastic environments such as mucus, heterogeneous microbial barriers, and polymer matrices. Unifying her work is a systems-level approach that seeks to understand how local structure governs transport and therapeutic action and how to strategically reshape those landscapes through formulation. Her lab integrates solid-state formulation, aerosol engineering, and transport modeling to advance treatment of respiratory diseases. A key focus is the formulation of biologics for inhalation: her team uses multifunctional excipients to tune particle surface properties and bulk solid behavior to optimize both protein stability and aerosol performance. Other projects include designing synergistic antibiotic formulations that maintain co-exposure in spatially complex infections and developing microbial colonization models to guide microbiome-targeted therapies. Dr. Brunaugh has led interdisciplinary efforts with support from the NIH, Cystic Fibrosis Foundation, FDA, PhRMA Foundation, and industry partners, and has previously practiced as a clinical pharmacist. These experiences shape her translational focus and enable her to bridge mechanistic insight and clinical impact across biologics, anti-infectives, and respiratory delivery
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Carbohydrate-Driven Control of Respirable Protein Powder Surfaces and Performance
Tuesday, November 11, 2025
9:00 AM - 9:30 AM CT