Bioanalytics - Chemical

(T0930-01-01) Evaluation of a Novel Solid Phase Extraction for the Determination of Oligonucleotides from Biological Matrices and Analysis Using UPLC-MS/MS

(M0930-01-06) Comprehensive LC-MS Analytical Assays for Antibody-Oligonucleotide Conjugate (AOC) and siRNA Linker-Payload Characterization

(M0930-01-07) Development and Validation of a Sensitive Method for Quantification of Acalabrutinib and ACP-5862 in Human Plasma Using HPLC‑MS/MS

(M1030-01-01) Comparison of Linker-Payload Cleavage Methods of the Antibody Drug Conjugate Anetumab-MMAE to Determine the Conjugated Payload MMAE Concentration by LC-MS/MS

(T1030-01-02) Evaluation of LC-MS Coupled with a Single Quadrupole Mass Spectrometer for Drug Concentration Analysis in Plasma Samples

(M1030-01-02) Scaled Net Analyte Signal Distance (SND) - A Leverage-Based In-Model Diagnostic for Iterative Optimization Technology (IOT) Algorithm

(T1030-01-03) Significant Species Differences in Buprenorphine Metabolism: A Pharmacokinetic Comparison of Metabolite Exposure

(M1030-01-07) Validation of Anti-Drug Antibody Assay for Multi-Domain Biologics for Human Clinical Studies

(T1130-01-02) Transforming Quantitative Sensitivity for Small Molecule Analysis Using a High-Resolution Workflow

(T1130-01-06) Species and Gender-Related Variations in Dehydroepiandrosterone Sulfate Biliary Excretion: A Comparative LC-MS/MS Analysis

(T1130-01-07) Metabolite Profiling and Identification Strategy for the First-In-Human Study

(T1230-01-01) Development and Validation of a Novel LC-MS/MS Method for the Simultaneous Quantification of Alvocidib and Its Glucuronide: Application to Pharmacokinetic and Tissue Distribution Study in Rats

(M1230-01-02) Bridging Strategy Methods for an Accelerated Late-Stage mAb

(T1230-01-03) Absorption, Distribution, Metabolism, and Excretion of ION775, a Hepatocyte-Targeting siRNA Designed to Silence APOC3 Expression, Evaluated After Single and Multiple SC Dose(s) in Mice and Monkeys

(M1230-01-06) Quantification of Tirzepatide in Rat Blood by a Sensitive and Robust UPLC-MS/MS Method: Development and Validation

(T1330-01-02) MRM Based Free Fatty Acids Profiling in Human Plasma and Serum Using LC-MS/MS

(T1330-01-03) LC/MS/MS Assays for Three Novel Oxazolidinones with Potential Anticonvulsant Effects and Their Application in Pharmacokinetic Studies in Rats

(M1330-01-03) Plasma and Gastrointestinal Tissue Analysis of Prednisolone in Mice Following LPS-Induced Inflammation

(T1330-01-06) Hidden Dangers: The Serious Risk of Adulterated Herbal Supplements to Patient Health

(M1530-01-01) Untargeted Lipidomics Identifies Distinct Metabolic Alterations in Huh-7 Hepatocellular Carcinoma Cells Receiving Monotherapy or Combination Therapy with Atorvastatin and Doxorubicin

(T1530-01-05) Evaluating Açaí Cytochrome P450 Inhibitors Using High-Resolution Mass Spectrometry and Machine Learning Based Biochemometric Analysis

(T1530-01-06) Development of an Ultra-sensitive and Highly Selective Method for Quantification of Monomethyl auristatin E (MMAE) in Human Plasma Using HPLC‑MS/MS