Discovery and Basic Research

(W0930-03-15) Amorphous Aprepitant Prepared by Spray-Freeze-Drying can be Stabilized with Low Viscosity HPC Grades

(T0930-03-15) Exploring Bacterial Peptidoglycan as a Vaccine Platform

(M0930-03-15) Synergistic Cannabichromene–Cannabidiol Co-Therapy Reprograms Signaling, Epigenetics, and Pharmacokinetics to treat Drug-Resistant Triple-Negative Breast Cancer

(T0930-03-16) Oxaliplatin Inhibits Oncogenic Signaling to Potentiate Radiation Response in Preclinical Models of Radioresistant Glioblastoma and Outperforms the Clinical Standard-of-Care Temozolomide

(M0930-03-16) Paclitaxel Nanomicelles in 2D Monolayer and 3D Multicellular Spheroid Models of Triple-Negative Breast Cancer

(M0930-03-17) Effect of Vasculotropic Dutch Amyloid Beta 40 on Blood-Brain Barrier (BBB) Endothelial Trafficking and Signaling

(W0930-03-17) Enhanced Transdermal Delivery of Tizanidine Using Novel Cavity Hydrogel-Forming Microneedles

(T0930-03-17) Targeted Chemoprevention of Ovarian Cancer Using a Redox-Sensitive PCQ-Gemcitabine Conjugate

(W0930-03-18) Aberrant Splicing of PI3Kδ Promotes Drug Resistance in Hematological Malignancies

(T0930-03-18) Accurate Quantification of DNA Methylation and Hydroxymethylation in Biosamples Using Liquid Chromatography–Tandem Mass Spectrometry

(M0930-03-18) Exofection as a Therapeutic Modality: Restoring P-gp Activity via Trophoblast-Derived Extracellular Vesicles in Neuroinflammatory Disorders

(W0930-03-19) Assessing the Relevance of Nw-Hydroxy L-Arginine to Inflammatory and Immune Checkpoint Molecules in Breast Cancer Based on Estrogen Receptor Status and Disease Progression

(M0930-03-19) Identifying the Targets of Ocular Tissue-Targeting RNA Aptamers by Proteome Integral Solubility Alteration (PISA) Assay

(T0930-03-19) Mesoporous Silica Nanoparticles-Based Radionuclide Therapy Demonstrates Immunomodulatory Effects and Enhanced Treatment Outcome in Peritoneal Cancer Model

(T0930-03-20) Dissolution Profile Control of Novel Ketoconazole Complexes Using Different Coformers

(W0930-03-20) Formulation of Freeze-Dried Self-Emulsifying Dual Oral Drug Delivery Systems in the Treatment of Breast Cancer

(M0930-03-20) Live Cell NanoLuciferase Assay Based Identification of Ligand Specific Monoclonal Anti-RAGE Antibody

(W0930-03-21) H-89 Exhibits Synergistic Antimicrobial Efficacy With Colistin Against Klebsiella pneumoniae Through Elevated ROS Level

(M0930-03-21) Hot-Melt Extruded Implants Loaded with Brinzolamide for Intravitreal Drug Delivery

(T1030-03-15) Coarse-Grained Molecular Dynamic Simulations of Protein-Membrane System

(M1030-03-15) Metformin Induced-Oxidative Stress Modulates Cellular Redox Homeostasis and Suppresses Cell Growth in Early and Late-Stage Prostate Cancer Cells

(W1030-03-16) Design and Biopharmaceutical Characterisation of Ciprofloxacin Ester Salts: Assessing Solubility and Permeability Dynamics through Molecular Descriptors

(T1030-03-16) Enhancing Transdermal Delivery of Salbutamol via Optimized Nanoemulsion Formulations: The Impact of Surfactant Selection and Component Ratios

(M1030-03-16) Method Development for Antimicrobial Efficacy Test in Anhydrous Based Products

(T1030-03-17) Breaking Barriers: Quinazoline-Scaffolded Kinase Inhibitors with Optimized Blood Brain Barrier Permeability to Treat CNS Malignancies

(M1030-03-17) Development of Monocarboxylate Transporter 4 Inhibitor/Docetaxel-Loaded Smart Layer-By-Layer Nanoparticles for Prostate Cancer Therapy

(W1030-03-17) Fabricating Inhalable PLGA Nanoparticles for Targeted Therapy in Non-small Cell Lung Cancer

(T1030-03-18) In Vivo Tissue Distribution of a Model PROTACs and Its Metabolites Following Subcutaneous Administration To Male Rats Via DESI - MS Imaging

(T1030-03-19) Calcium-Enhanced Chromatography for the Purification of Polar Ammonium and Peptide Compounds

(W1030-03-19) Comparison of Exosome Isolation Methods for the Analysis of a Disease Biomarker in Serum and Urine by PCR Methodologies

(M1030-03-19) In Silico Modeling Helps Predict Antibody Solution Behavior with Charged Cargo Moieties

(W1030-03-20) Assessing the Impact of Varying DMSO Concentrations on Immunogenicity Readouts in Macrophage and Dendritic Cell-Based In Vitro Models

(M1030-03-20) Development and Implementation of a Ferret Venous Catheterization Model for Pharmacokinetic Studies

(T1030-03-20) Therapeutic Potential of Dual-Action Antibody-Drug Conjugates as a Novel Strategy for Cancers Heterogeneously Expressing RON Receptor Tyrosine Kinase

(W1030-03-21) Improved Model Development for Accelerated Colon Polyp Growth in Pirc Rats

(M1030-03-21) In Vitro Evaluation of the Effect of Polymer Concentration on the Mechanical Properties and Drug Release of Dextromethorphan Hydrobromide from Polyvinyl Alcohol Cryogels

(T1030-03-21) Interactome between Exopolysaccharide, Poly-(1- > 6)-β-N-acetylglucosamine and Proteins in Staphylococcus Epidermidis Biofilms by Live Cell Proximity Labeling

(T1130-03-15) Development of a 96-Well Microplate Reader-Based Method for High-Throughput Screening of Antiplatelet Effects in Rat Platelet-Rich Plasma for Drugs and Herbal Components

(M1130-03-15) Method Development and Validation of Liquid Chromatography–Tandem Mass Spectrometry for SLP-1A6 in Rat Plasma

(W1130-03-15) NGS-Based Platform for Detecting Lentiviral Insertion Sites and Genomic Integration

(W1130-03-16) Homologous Recombination Is Essential for DNA Damage-Induced Regeneration of Germline Stem Cells in the Drosophila Testis Niche

(T1130-03-16) Integration of RNA-Seq and ATAC-Seq Unveils Chromatin Accessibility and Gene Expression Changes in Acute Myeloid Leukemia Cells

(T1130-03-17) A Novel Simulated Plant Based IVG Cervical Mucus Formulation for Sperm Functional Assays with Optimized Spinnbarkeit and Viscosity

(M1130-03-17) Growth and Differentiation Factor 5: A Therapeutic Path for Chondrogenic Progenitor Cell-Based Cartilage Regeneration to Prevent Post-Traumatic Osteoarthritis

(W1130-03-17) Molecular Dynamics Insights into Cryoprotectant-Mediated Stabilization of Amphotericin Liposomes During Freeze-Drying: A Comparative MD and SA-MD Study

(M1130-03-18) Development of Multitargeted Inhibitor, IND-2, for Prostate Cancer Therapy

(T1130-03-18) Next-Generation Sequencing Based RNA-Seq Discover the Differentially Expressed Genes and Pathways of Systemic Lupus Erythematosus

(W1130-03-18) Study on the Anti-Lipid Accumulation Effects of Compounds Derived from Herbs Based on High-Throughput Intracellular Lipid Droplet Phenotypic Analysis

(W1130-03-19) A Novel Plant-Based Orally Disintegrating Films Platform Using Hydroxypropyl β-Cyclodextrin for Pharmaceutical Product Development of Poorly Soluble Drugs

(M1130-03-19) Targeting LSD1 Results in the Upregulation of ASGPR1, Offering a Promising Avenue to Improve the Therapeutic Potential of LYTAC-Driven Extracellular Protein Degradation in Liver Cancer

(T1130-03-19) Ultrasensitive LC-MS/MS Method Enables a Thorough Pharmacokinetic Investigation of Low-Dose Semaglutide Following Oral and Subcutaneous Administration in Healthy Subjects

(W1130-03-20) Discovery of Mitochondria Targeted Non-apoptotic Cell Death Inducers against Resistant Triple-Negative Breast Cancer

(T1130-03-20) Enhancing Drug Penetration Across the Blood Ocular Barrier Using Peptide Transporters: Expression and Pharmacokinetic-Based Analysis

(M1130-03-20) Transport Characterization of Tramadol in an Ex Vivo Blood-Brain Barrier Model Based on Microimpalement of Vessels

(T1130-03-21) From Disorder to Order: Structural Evolution of Solid-State Phases in Pravastatin Sodium via a Liquid Crystalline State

(M1130-03-21) Mitigation of Non-Specific Adsorption of Peptides using Inert Surfaces

(M1230-03-15) Biotin-Targeted Pluronic/Bile Salt Mixed Micelles for Enhanced Bioavailability of Therapeutic peptide

(W1230-03-15) Development of a Plate-Based Assay for the Quantitation of Tenecteplase Activity in Plasma Samples

(T1230-03-15) In Silico Screening Study of Potential Flavonoids as ADAMTS-5 Exosite Inhibitors for the Treatment of Knee Osteoarthritis

(W1230-03-16) Evaluation of the Selectivity of In Vitro Dissolution Absorption System 2 (IDAS2) Through Immediate-Release and Immediate-Extended Bilayer Formulations of BCS Class I Drugs

(T1230-03-16) Formulation and Characterization of Spray-Dried Dermaseptin for Pulmonary Delivery in Lung Cancer Therapy

(T1230-03-17) Meta-Analysis of the Across-Species Pharmacokinetics of Metronidazole with a Minimal Physiologically-Based Pharmacokinetic Model

(W1230-03-17) Peptide-Based Nanoplatform for Improved Cas9 RNP Delivery and Editing

(M1230-03-17) Stabilizing mRNA Lipid Nanoparticles for Aerosolized Delivery Using Excipients

(T1230-03-18) Lateral Transport in Anisotropic Membrane during Permeation Study with Diffusion Cell

(M1230-03-18) Whole Genome Sequencing and Analysis of Manzamine Producer Micromonospora sp. M42

(T1230-03-19) Comparative Evaluation of the Efficacy of Two Novel Trifunctional Compounds for Glaucoma

(M1230-03-19) Mechanistic Insights into Mitochondrial Targetability of PEGylated Fluoroalkyls in Drug Delivery

(W1230-03-19) Pharmacokinetics and Biodistribution of FVIII Containing LysoPS Nanoparticle Following IV Administration

(T1230-03-20) A Novel Trifunctional Donor Enhances Nrf2 Activation and Preserves Retinal Integrity Under Oxidative Stress

(W1230-03-20) AI in Action: Accelerating Co-Crystal Design Using Machine Learning

(M1230-03-20) Pathological and Demographic Determinants of SARS-CoV-2-mediated Dysregulation of Drug Processing Pathways

(T1230-03-21) Application of Lecithin (PL90) and Poloxamer 188 in SLC Transporter-Mediated Drug Interaction Studies

(W1230-03-21) Biological Evaluation of zq-1-68, a Novel Dual-Targeting Tubulin/HDAC Inhibitor in Metastatic Castration-Resistant Prostate Cancer

(M1230-03-21) Enhancing Bioanalytical Lab Efficiency and Compliance Through an Integrated Lab Execution System (LES)

(M1330-03-15) Extracellular Vesicle Transcriptomic Analysis for Understanding Muscle Aging under the Influence of Microgravity

(T1330-03-15) Prediction of DNA-Targeting Anti-Cancer Therapeutics Using Machine Learning-Guided Molecular Docking

(M1330-03-16) Benchtop MALDI Imaging of Human Tonsil Proteins Using IHC Probes

(T1330-03-16) Implementing the Latest Available Technologies in High Throughput through In Vitro ADME DMPK

(M1330-03-17) Harnessing Mass Spectrometry Approaches to Quantify Glycan Composition at the Blood-Brain Barrier

(T1330-03-18) Development of a Pulsed Current Iontophoresis System for Transdermal Administration of Palonosetron Hydrochloride: Exploring the Potential for a Shift Toward At-Home Medical Care

(M1330-03-18) Permeability of Small Molecular Weight Compounds and Macromolecules through Ex Vivo Rabbit Ocular Tissues

(M1330-03-19) Development and Validation of a UPLC Assay for Quantification of a Novel Anti-CRPC Agent PC257 for Preformulation and In Vitro Metabolism Studies

(T1330-03-19) Targeting T-Cell Exhaustion in 3D-Patient-Derived Triple Negative Breast Cancer Organoids and PDx Mice Models Using Novel Calcium Nanoparticles

(M1330-03-20) RP-HPLC Method Development for the Simultaneous Estimation of Trazodone and Gabapentin in Bulk Drug

(T1330-03-20) Synthesis, Structural Characterization, and Inhibitory Effects of Caffeic Acid Phenethyl ester (CAPE) Derivatives on Human Multiple Myeloma Cell Growth

(M1330-03-21) Discovery of Pan-EphB Tyrosine Kinase Inhibitors to Reverse Metabolic Syndrome in Obese Mice

(T1330-03-21) Ultrasound Responsive Violacein Loaded Liposomes for Sonodynamic Therapy against Broad-Spectrum Bacteria and Melanoma: In Vitro Studies

(T1430-03-15) Identification of EphB1/2 Tyrosine Kinase Inhibitors for Chemotherapy-Induced Peripheral Neuropathic Pain

(T1430-03-16) Evaluation of a Toll-Like Receptor 7/8 Antagonist for Anti-Inflammatory Immunotherapy

(T1430-03-17) High-Throughput, Multiplexed CRISPR-Cas13a Assay for Simultaneous Detection of Tuberculosis, HIV, Malaria, and TB Drug-Resistance Markers Using CARMEN

(M1430-03-17) Novel Synergistic TKI Combination Induces Immunogenic Cell Death in Colon Cancer with BRAF and KRAS Mutations

(M1430-03-18) Developing a Liposomal Ciprofloxacin Formulation Using Passive and Active Loading Strategies for Enhanced Ocular Delivery in Bacterial Endophthalmitis

(T1430-03-18) Effect of Intranasally Administered Midazolam, Diazepam or Lorazepam on Neuroinflammation in Acute Seizures Mice

(M1430-03-19) Exploring Mitochondrial Involvement in Persistent Fat Accumulation of Lipedema

(T1430-03-19) Selenium-Functionalized Sulfated Hyaluronic Acid (sHASe): A Novel Multi-Targeted Therapeutic Strategy for Overcoming Therapy Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

(T1430-03-20) A Rationally Designed Orally Active Peptidomimetic-Targeting EGFRs for Non-Small Cell Lung Cancer

(M1430-03-20) Enhancing Oral Bioavailability in Preclinical Dog PK Studies Using Ball Milling Technology

(M1430-03-21) In Vitro Evaluation of Polyvinyl Alcohol (PVA) Cryogels for Sustained Release of Anionic and Cationic Drugs

(T1430-03-21) Role of Co-Occurring Herbs on Toxicity of Radix Aconiti Lateralis Containing TCM Formulae

(T1530-03-15) Dual Immunomodulatory and Neuroprotective Effects of Urea-Based Soluble Epoxide Hydrolase Inhibitor

(M1530-03-15) Evaluating Physicochemical Properties of Cyclic Peptides and Their Interactions with Bile Acids Using Micellar Electrokinetic Chromatography

(T1530-03-16) A Comparative Study of Product Recovery in Laboratory-Scale Spray Dryers: Standard Cyclone vs. the Discovery Module

(M1530-03-16) On-Demand Endogenous Nanoparticle Based Cargo Loading of Extracellular Vesicles for Therapeutic Delivery

(T1530-03-17) Lattice Based Model to Study Drug Diffusion through Excipient Matrix

(M1530-03-17) Unveiling PNAG Dynamics in Bacterial Biofilms through Microfluidics and Fluorescence Microscopy

(M1530-03-18) A Novel Therapeutic Approach for Treatment of Taxane-Resistant Prostate Cancer

(T1530-03-18) Ionic Liquid-Based Dissolving Microarray Patches for Controlled Release of Isoniazid: A Proof-of-Concept Study

(T1530-03-19) Respiratory and Genomic Effects Induced by Phosphine Gas Exposure: Insights from Mouse Model to Identify Therapeutic Targets

(T1530-03-20) Evaluation of Histone Deacetylase-6 (HDAC-6) Inhibitor Tubacin on 3D Midbrain Neurospheres: A New Therapeutic Avenue for Parkinson’s Disease

(M1530-03-20) Overcoming Intracellular Delivery Challenges of Small- and Large-Molecule Through First-in-Class Macropinocytosis Activators

(T1530-03-21) Study on the Immunomodulatory Effect of Major Plasma Components of Fufang Shengdi Granules in Imiquimod-Induced Psoriasis Mice